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Microscopic eukaryotic green algae play an essential role in converting solar energy into chemical energy through the process of photosynthesis, and recently these microorganisms have gained attention as a potential source of renewable fuel .

In addition to energy production, micro algae can produce a variety of

other bioproducts including nutraceuticals and recombinant protein s such as  industrial enzymes or therapeutics

Using the green algae Chlamydomonas  reinhardt ii, demonstrated that algae are capable of expressing, folding, an d accumulating arrange of human therapeutic proteins in the chloroplast , recombinant proteins also can be secreted from algae in culture medium .

Algae require only trace minerals, fertilizer, and sunlight to be grown at scale, giving them the potential to prod cue recombinant proteins, including therapeutics , very inexpensively .

Although cost can be a signi´Čücant factoring the prod unction of protein- based therapies , producing  unique  classes of therapeutically relevant proteins in algae offer the potential to produce a number o f novel proteins because of the unique biochemical environment of the chloroplast.

Algae biomass accumulation is extremely rapid, and the entirety of biomass can be utilized for edible vaccine production in photosynthetic organism.

Enclosed bioreactor can be used for higher biomass yield production. Green algae such as C.reinhardtii are generally recognized as safe (GRAS) by the PDA.

From the research available to date, it is clear that algae can produce complex vaccine antigen and therapeutic protein that can elicit immunogenic and therapeutic response.